Executive Director, Late Development Team Leader

Company: Jazz Pharmaceuticals
Location: Philadelphia
Posted on: June 4, 2025

Job Description:

If you are a current Jazz employee please apply via the Internal Career site.
Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to
transform the lives of patients and their families. We are dedicated to developing
life-changing medicines for people with serious diseases - often with limited or no
therapeutic options. We have a diverse portfolio of marketed medicines, including leading
therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments.
Our patient-focused and science-driven approach powers pioneering research and development
advancements across our robust pipeline of innovative therapeutics in oncology and
neuroscience. Jazz is headquartered in Dublin, Ireland with research and development
laboratories, manufacturing facilities and employees in multiple countries committed to
serving patients worldwide. Please visit

for more information.
Brief Description:The Late Development Team Lead (LDTL) is a critical role in the organization that has a significant impact on the late product lifecycle of a product or platform of products. The LDTL is accountable for leading the Late Development Team (LDT) in establishing and executing on a global product(s) strategy, which integrates scientific rationale, clinical development, nonclinical development, regulatory, medical, commercial input, CMC, legal and other business strategies.The LDTL provides strategic and operational leadership to one or more LDT(s) to progress and de-risk the product from proof of concept (POC) to approval, aligned with the Target Product Profile. The LDTL serves as the single point of accountability for the product. To be successful, the LDTL must balance a focus on deep science and innovation, with speed and potential program and regulatory uncertainty or risks as well as maximizing over value for our patients. The LDTL partners with functional area leaders to ensure that the LDT has necessary resources and capabilities to execute on the approved integrated product development plan. The LDTL is responsible for representing the product strategy at Jazz governance reviews.For certain programs, an alliance may be established with a 3rd party. In such cases, the LDTL shall establish a collaborative, empowering relationship with the 3rd party to enable effective facilitation and coordination. Awareness of cultural and organizational matters associated with the 3rd parties is also important including working with Jazz Alliance Management.Preferred qualifications for this position include:A strong executive with superior cross-functional leadership and collaboration skills, highly effective influencing skills, and the ability to operate across multiple geographies. A strong scientific understanding is essential, and candidates will also have proven experience leading a program or function in late-stage drug development, preferably a highly complex and/or high priority project where risk and program speed and value had to be balanced. Success in this critical role will provide the opportunity for significant professional growth.Essential Functions:

• Serve as the leader of one (or more) cross functional LDT(s) with accountability for product strategy and operational execution from POC to approval.
• Establish a vision and strategy for the product with the LDT, and relevant functional matrix teams.
• Leverage input from all critical functions to identify and evaluate strategic global product development opportunities that optimize the value for our patients through optimal balance of risk, timelines, cost and revenue.
• Participate in the Long Range Plan (LRP) process and approve underlying assumptions resulting in articulate strategies and plans that align with Jazz's mission and approach.
• Develop global Integrated Product Development Plans (iPDPs) for governance approval and provide oversight for LDT contributions for regulatory filings (NDA, labeling).
• Lead and drive team accountability and effectiveness by setting clear expectations for the LDT and team members' roles and responsibilities. Promote team cohesiveness to optimize performance, mediating conflict resolution and embedding Diversity, Equity, Inclusion, and Belonging.
• Provide strategic guidance and support to LDT functional matrix teams and activities that are executed in matrix and functional channels (e.g. clinical development, technical operations, commercial, regulatory).
• Mentor team members, constructively challenge strategies, set expectation for decision quality and provide performance review input for key positions on the LDT.
• Mobilize and align the organization to execute on the approved product strategy, including coordination and synchronizing activities with other LDTs and/or functional matrix teams.
• Accountable for project budget, timelines and resource requirements in collaboration with the team members, Project Management and finance.
• Collaborate with functional heads to confirm required roles and nomination of key LDT members.
• Proactively engage with leaders in the organization to establish and align on development strategy, through identification of alternatives, tradeoffs, and interdependencies to optimize the value of the product, and prepare for stage gate presentations to the Early Development Project Review Committee (EDPRC) or Development Project Review Committee (DPRC) and Portfolio Governance Committee (PGC).
• Ensure the timely escalation of realized risks and issues to senior leaders, DPRC and other review/decision-making/governance committees.
• May be required to take on additional responsibility for external collaborations and/or corporate strategic projects with high visibility and expanded team leadership responsibilities including participation in external due diligence for in-licensing opportunities. This may include participation or leadership on Strategic Partnership Joint Governance Committee and/or Working Teams.
• Contribute to disease area assessments and other portfolio level cross-molecule initiatives.
• Partner with relevant functions to develop effective working relationships both internally and with external key stakeholders (development partners, key opinion leaders, advocacy groups, etc.).
• As appropriate, participate in ongoing development and enhancement of cross-functional team structures, processes, systems, and other tools and resources.Required Knowledge, Skills, and Abilities:
  • +15 years global multi-disciplinary drug development experience in the pharma/biotech industry with key roles or leadership in development programs and a proven track record of innovation and balancing program risks with speed.
  • Proven experience as a successful, decisive leader in a strategic multi-functional environment with a track record of delivering results through effective matrix teams and peer leadership.
  • Proven ability to define and communicate a compelling long-term vision and engage and lead global cross-functional teams to develop an aligned strategy
  • Prior experience in large scale late phase Solid Tumor Oncology drug development and regulatory submissions (NDA, MAA, JNDA) with proven ability to lead multiple highly complex and/or high priority projects.
  • Experience managing and/or leading collaborations, alliances, or other relationships through influencing without direct authority, creating effective relationships with peer counterparts in an alliance.
  • An effective problem solver with an entrepreneurial mindset who can find creative solutions to drug development challenges.
  • Ability to synthesize different points of view to make sound, timely and objective decisions. Cross-cultural and cross-organizational management and collaboration skills.
  • Proven capability to lead, motivate, inspire without authority in a diverse, global, cross-functional matrix structure
  • Demonstrated leadership and action in diversity and inclusion
  • Independent, self-motivated individual with a highly entrepreneurial style coupled with collaborative and positive leadership
  • Strong and influential communicator: exceptional influencing skills that demonstrate strong thought partnership and create effective relationships with internal and external stakeholdersRequired/Preferred Education and Licenses:
    • Advanced degree (MD, PhD, PharmD) required Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law. FOR US BASED CANDIDATES ONLYJazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $252,000.00 - $378,000.00Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: .

Keywords: Jazz Pharmaceuticals, Bethlehem , Executive Director, Late Development Team Leader, Executive , Philadelphia, Pennsylvania