Associate Director to Senior Director, PMO Capacity Management Lead

Company: Incyte Corporation
Location: Wilmington
Posted on: January 14, 2026

Job Description:

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. Director, PMO (Project Management Office) Capacity Management Lead will standardize processes and drive key strategic data/systems-based projects while being responsible for data quality, data maintenance and data analysis for various capacity management related initiatives. Must have a solid understanding of business operations, financial processes, and resource management concepts. This role will provide support and guidance to key R&D partners on capacity management systems, tools, data, and processes. You will lead the design, and support the development and delivery, of various activity-based models within our Planisware system. Key Responsibilities Clinical Cost Modeling: Lead the creation of robust cost models for clinical trials, factoring in variables such as patient recruitment, site management, drug supply, and regulatory requirements. Refine cost models for clinical trials, incorporating financial assumptions and benchmarks. Activity-Based Forecasting: Oversee the development of forecasts for clinical trial activities, incorporating timelines, resource demands, and project milestones to guide R&D planning. Direct the calculation of estimate to complete (ETC) while leveraging remaining timeline assumptions to ensure accurate projections and forecasts. Planisware Algorithm Oversight: Manage and validate Planisware algorithm models for financial forecasting, ensuring transparency in inputs (e.g., cost drivers, trial milestones), calculations (e.g., cost allocation formulas), and assumptions. Maintain clear documentation and reporting of Planisware algorithm inputs, calculations, and assumptions to support auditability and stakeholder confidence. Strat Plan, Budget, and Forecasts: Support annual budgeting and forecasting processes with workforce related financial insights. Support the alignment of financial and resource data with project and study assumptions for the annual Strategic Planning and Budget Processes. Provide information necessary to support quarterly Forecast and Monthly Planning and Control Processes. Orphan Drug Credits: Oversee the tracking and optimization of tax credits and incentives for orphan drug development, maximizing financial benefits Business Analysis and Reporting: Prepare and deliver recurring and ad-hoc financial reports to finance leadership and business partners. Provide actionable financial insights through variance analysis, cost-benefit analysis, scenario planning, and other reporting solutions. Translate complex financial/resource management data into clear, actionable insights for both finance and non-finance audiences. Analyze headcount, labor cost, and utilization data to support resource planning Cross-Functional Collaboration: Partner with Finance (FPA), clinical operations, regulatory, and development project management teams to ensure forecasting aligns with trial milestones and operational needs. Collaborate with the Business Intelligence Resources within the PMO Team to deliver requirements and develop dashboards to manage resource spending and capacity planning. Process Improvement and Oversight: Oversee the design, implementation, and standardization of forecasting and budgeting processes, ensuring consistency, efficiency, and compliance with industry best practices. Lead initiatives to identify inefficiencies, streamline workflows, and implement process enhancements to improve forecasting accuracy and budgeting effectiveness. Additional Responsibilities Advanced Analytics and Forecasting Innovation o Collaborate with the internal Artificial Intelligence Team to explore innovative solutions, such as migrating forecasting models from Planisware to AI-driven platforms for improved algorithm development and continuous refinement. o Drive the adoption of AI-powered processes to optimize resource allocation, predict clinical trial forecasts, and enhance decision-making processes. Work with other internal teams to develop AI-based forecasting models that adapt over time, leveraging machine learning to refine predictions based on historical data and real-time inputs. o Investigate alternative design approaches for forecasting and capacity management, ensuring scalability, flexibility, and alignment with organizational goals. Lead discussions on system transitions, model redesigns, and the incorporation of advanced analytics to support long-term strategic objectives. Qualifications Bachelor’s degree in Finance, Accounting, Business Administration, Life Sciences, or a related field (MBA, CPA, or advanced degree preferred) 10 years of experience in financial planning, forecasting, or budgeting within pharmaceutical R&D or a related industry. Proven expertise in clinical cost modeling, activity-based forecasting, portfolio management, and process improvement. Experience with Planisware or similar systems for resource and financial management. Skills and Competencies: Deep understanding of pharmaceutical R&D processes, including clinical trial phases and clinical trial budgeting models. Strong analytical and financial modeling skills, with proficiency in advanced analytics and forecasting algorithms. Experience working with AI-based models for forecasting, including knowledge of machine learning frameworks and data science principles. Ability to ensure transparency through documentation of forecasting models, including inputs, calculations, and assumptions. Ability to partner with technical and operational teams to drive financial insight while managing multiple priorities Strong business acumen with the ability to work independently and manage multiple priorities. Understanding of project-based accounting or resource planning principles. Excellent leadership, communication, and stakeholder management skills. Technical Proficiencies: Advanced proficiency in Planisware, ERP systems, and financial reporting tools; Proficient in Excel and financial reporting tools; experience with SQL, Power BI, Tableau, or similar platforms preferred. Familiarity with financial systems (e.g., Oracle, SAP, Adaptive Insights, Hyperion) and project costing concepts. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate. During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte’s data protection officer, and your supervisory authority (if applicable).

Keywords: Incyte Corporation, Bethlehem , Associate Director to Senior Director, PMO Capacity Management Lead, Accounting, Auditing , Wilmington, Pennsylvania